De Fermo operates in Abruzzo, the rugged wine region of Central Italy where Mediterranean warmth meets Apennine altitude. The winery focuses on indigenous varieties that define the territory: Pecorino for white wines of mineral precision, and Montepulciano for reds of structure and depth. The Don Carlino Pecorino and Concrete Montepulciano d'Abruzzo anchor the portfolio, both rated 92 by Wine Enthusiast. The Le Cince Cerasuolo d'Abruzzo Superiore—a rosé expression of Montepulciano—adds a third dimension, rated 91. These wines reflect Abruzzo's volcanic soils and continental climate, where Montepulciano develops tannin and acidity, and Pecorino thrives in cooler microclimates. De Fermo's selections demonstrate the region's capacity for wines of balance and terroir-driven character.