Notre Dame de Cousignac produces wines from the Southern Rhône, a region defined by warm Mediterranean conditions and ancient granite soils. The winery's portfolio centers on Grenache-based blends—the signature grape of southern Rhône reds—layered with Syrah, Mourvèdre, and regional varieties like Cinsault and Carignan. The Vacqueyras and Lirac, both appellations known for structured, age-worthy reds, showcase the winery's command of these terroirs, while the Vinolithic Côtes-du-Rhône-Villages offers a more approachable entry point without sacrificing complexity. These wines have been assessed by Wine Spectator, Wine Enthusiast, and Wine Advocate. The house style emphasizes the dark fruit and spice character typical of Southern Rhône blends, with the mineral backbone that granite-based vineyards impart.