Santini operates in Emilia-Romagna, the historic wine region of Northern Italy known for its food-centric culture and distinctive red wines. The winery focuses on Sangiovese, the region's signature grape variety—a wine of structure, acidity, and earthy depth that pairs naturally with the region's rich culinary traditions. Santini's portfolio centers on two expressions: Cornelianum Sangiovese, a wine that captures the varietal's core character, and Cornelianum Sangiovese Riserva, a more concentrated iteration aged to greater complexity. Both wines have been assessed by Wine Enthusiast and Wine Spectator, reflecting their standing within the critical conversation around Northern Italian Sangiovese.